Product Details
Product Name:
– 6-Diazo-5-oxo-L-nor-Leucine
Catalog Number:
– D60563
Field of Application:
– 6-Diazo-5-oxo-L-nor-Leucine (DON) is a glutamine analog that inhibits glutaminases (Ki = 6 ?M) and other glutamine-utilizing enzymes, including cytidine triphosphate synthase (CTPS), which uses glutamine in the synthesis of CTP.1,2,3 DON is commonly used in cells or tissues but its use in whole animals is limited by its teratogenicity.
CAS:
– [157-03-9]
Formular:
– C6H9N3O3
SMILES:
– C(C[C@@H](C(=O)O)N)C(=O)C=[N+]=[N-]
