Product Details
Product Name:
– TPX-0022(CSF1R-IN-2)
Catalog Number:
– D46183
Field of Application:
– TPX-0022 (CSF1R-IN-2) is a potent inhibitor of MET/CSF1R/SRC with enzymatic kinase inhibition IC50s of 0.14 nM, 0.71 nM and 0.12 nM, respectively. TPX-0022 modulates the tumor immune microenvironment in preclinical models.
CAS:
– [2271119-26-5]
Formular:
– C20H20FN7O2
SMILES:
– FC1C=CC2=C(C=1C#N)CN(CC)C1C=CN3C(=C(C(N)=N3)C(NC[C@H](C)O2)=O)N=1
