ASP2453

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SKU D47351-10 mg Category
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Product Details

Product Name:

– ASP2453

Catalog Number:

– D47351

Field of Application:

– ASP2453 is a potent, selective and covalent KRAS G12C inhibitor. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM.

CAS:

– [2241719-73-1]

Formular:

– C40H48F3N7O4

SMILES:

– C1N(C2=NC(OC3CCN(CCCOC)CC3)=NC3C2=CC(=C(C=3OCC(F)(F)F)C2C3=C(C=CC=2C)NN=C3)C2CC2)CCC2(CN(C(=O)C=C)C2)C1

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