Product Details
Product Name:
– Bisindolylmaleimide VIII (acetate)
Catalog Number:
– D65451
Field of Application:
– Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC. Bisindolylmaleimide VIII acetate has IC50s of 53, 195, 163, 213, and 175 nM for PKC-?, PKC-?I, PKC-?II, PKC-?, PKC-?, respectively[1]. Bisindolylmaleimide VIII acetate facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases[2].
CAS:
– [138516-31-1]
Formular:
– C26H26N4O4
SMILES:
– CN1C=C(C2=C(C(NC2=O)=O)C3=CN(C4=CC=CC=C34)CCCN)C5=CC=CC=C51.CC(O)=O
