Product Details
Product Name:
– BI-3406(SOS1-IN-2)
Catalog Number:
– D39083
Field of Application:
– BI-3406 (compound I-6) is a potent, selective and orally active inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with IC50 of 6 nM. BI-3406 reduces the formation of GTP-loaded KRAS, and inhibits MAPK pathway signaling. BI-3406 exhib
CAS:
– [2230836-55-0]
Formular:
– C23H25F3N4O3
SMILES:
– CC1=NC2=CC(=C(C=C2C(=N1)NC(C)C3=CC(=CC(=C3)N)C(F)(F)F)OC4CCOC4)OC
