Product Details
Product Name:
– PT2977
Catalog Number:
– D31023
Field of Application:
– PT2977 (MK-6482) is an orally active and selective HIF-2? inhibitor with an IC50 of 9 nM. PT2977, as a second-generation HIF-2? inhibitor, increases potency and improves pharmacokinetic profile. PT2977 is a potential treatment for clear cell renal cell carcinoma (ccRCC)[1].
CAS:
– [1672668-24-4]
Formular:
– C17H12F3NO4S
SMILES:
– N#CC1C=C(OC2C3[C@H]([C@H]([C@@H](O)C=3C(S(=O)(C)=O)=CC=2)F)F)C=C(F)C=1
