Product Details
Product Name:
– BMX-IN-1
Catalog Number:
– D23998
Field of Application:
– BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Brutons tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
CAS:
– [1431525-23-3]
Formular:
– C29H24N4O4S
SMILES:
– C=CC(NC1C(C)=CC=C(N2C(=O)C=CC3=C2C2=CC(C4=CC=C(NS(=O)(C)=O)C=C4)=CC=C2N=C3)C=1)=O
