Product Details
Product Name:
– CCG-50014
Catalog Number:
– D22819
Field of Application:
– CCG-50014 is the most potent against the regulator of G-protein signaling protein type 4 (RGS4) (IC50 =30 nM) and is >20-fold selective for RGS4 over other RGS proteins. CCG-50014 binds covalently to the RGS, forming an adduct on two cysteine residues located in an allosteric regulatory site. CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test.
CAS:
– [883050-24-6]
Formular:
– C16H13FN2O2S
SMILES:
– FC1C=CC(CN2C(=O)SN(C3C=CC(C)=CC=3)C2=O)=CC=1
