Product Details
Product Name:
– Danicopan (ACH-4471)
Catalog Number:
– D11082
Field of Application:
– Danicopan (ACH-4471, ACH-0144471) is a highly potent, orally active Factor D inhibitor with Kd of 0.54 nM, inhibits the proteolytic activity of purified Factor D against substrate Factor B in complex with C3b, blocking production of Bb fragment IC50 of 15 nM.
CAS:
– [1903768-17-1]
Formular:
– C26H23BrFN7O3
SMILES:
– N(C(CN1C2=C(C=C(C3=CN=C(C)N=C3)C=C2)C(C(C)=O)=N1)=O)1C[C@@H](F)C[C@@H]1C(NC1=NC(Br)=CC=C1)=O
