(±)-BAY-1251152

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SKU D60039-50mg Category
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Product Details

Product Name:

– (±)-BAY-1251152

Catalog Number:

– D60039

Field of Application:

– AY-1251152 is a potent and highly selective PTEF/CDK9 inhibitor. BAY1251152 binds to and blocks the phosphorylation and kinase activity of CDK9, thereby preventing PTEFb-mediated activation of RNA Pol II and leading to the inhibition of gene transcription of various anti-apoptotic proteins. This may cause cell cycle arrest and induce apoptosis, which may lead to a reduction in tumor cell proliferation.

CAS:

– [1610358-53-6]

Formular:

– C19H18F2N4O2S

SMILES:

– S(C)(CC1C=CN=C(C=1)NC1C=C(C(=CN=1)F)C1C=CC(=CC=1OC)F)(=N)=O

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