Product Details
Product Name:
– 4-Hydroxyretinoic acid
Catalog Number:
– D66071
Field of Application:
– 4-Hydroxyretinoic acid (4-HRA) is a naturally occurring retinoid derivative with diverse biological effects. 4-Hydroxyretinoic acid is formed from retinol catalyzed by cytochrome P-450 isozyme(s), and is mainly metabolized by the liver in the body. 4-Hydroxyretinoic acid also serves as the substrate for human liver microsomal UDP-glucuronosyltransferase(s) and recombinant UGT2B7. 4-Hydroxyretinoic acid regulates gene expression and cell differentiation via binding to nuclear receptor RAR (Retinoic Acid Receptor), and activates RARs and RXR-alpha, to induce cancer cell apoptosis. In addition, 4-Hydroxyretinoic acid is also involved in various physiological processes such as immune regulation, neuroprotection, and anti-oxidation.
CAS:
– [66592-72-1]
Formular:
– C20H28O3
SMILES:
– OC(/C=C(/C=C/C=C(/C=C/C1=C(C)C(O)CCC1(C)C)C)C)=O
