Product Details
Product Name:
– Afatinib (BIBW2992)
Catalog Number:
– D1024
Field of Application:
– BIBW2992 (Afatinib, Tomtovok, Tovok) irreversibly inhibits EGFR/HER2 including EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.
CAS:
– [439081-18-2]
Formular:
– C24H25N5O3FCL
SMILES:
– CN(C)CC=CC(=O)NC1=C(OC2COCC2)C=C3C(=C1)C(=NC=N3)NC4C=C(Cl)C(F)=CC=4
