Product Details
Product Name:
– AOH1996
Catalog Number:
– D60479
Field of Application:
– AOH1996 is a proliferating cell nuclear antigen (PCNA) inhibitor. AOH1996 enhances PCNA and RPB1 interaction and interferes with TRC resolution and induces DNA double-stranded breaks in a transcription dependent manner. AOH1996 almost completely inhibits the growth of xenograft tumors without causing any discernible toxicity to experimental animals.AOH1996 has superior metabolic stability as compared to the?AOH1160?parent molecule.?
CAS:
– [2089314-64-5]
Formular:
– C26H22N2O4
SMILES:
– O(C1C=CC=C(C=1)OC)C1=CC=CC=C1NC(CNC(C1=CC=CC2C=CC=CC1=2)=O)=O
