Product Details
Product Name:
– AP1189 acetate
Catalog Number:
– D65879
Field of Application:
– AP1189 is a biased agonist at receptors MC1 and MC3. AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages. No melanogenesis was induced by AP1189 in B16-F10 melanocytes. In vivo, oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ?3-fold.
CAS:
– [959850-74-9]
Formular:
– C16H18N6O4
SMILES:
– N1(C2C=CC=CC=2[N+]([O-])=O)C(=CC=C1)/C=C/C=N/NC(N)=N.OC(=O)C
