Product Details
Product Name:
– AZ194
Catalog Number:
– D60184
Field of Application:
– AZ-194 is a first-in-class, orally active inhibitor of CRMP2-Ubc9 interaction and inhibitor of NaV1.7 (IC50=1.2 ?M). AZ194 blocks SUMOylation of CRMP2 to selectively reduce the amount of surface-expressed NaV1.7. Antinociceptive effects[1].
CAS:
– [2241651-99-8]
Formular:
– C34H31F2N3O3
SMILES:
– O=C(N1CCC(C2=NC3=CC=CC=C3N2CC4=CC=CC(F)=C4)CC1)C5=CC=C(OCC6=CC=CC(F)=C6)C(OC)=C5
