Product Details
Product Name:
– BTdCPU
Catalog Number:
– D32550
Field of Application:
– BTdCPU is an activator of HRI. The eIF2-alpha kinase HRI is a novel therapeutic target in multiple myeloma. Combination therapy with rapamycin, an mTOR inhibitor, and BTdCPU, an activator of HRI, demonstrated additive effects on apoptosis in dex-resistant cells. Thus, specific activation of the eIF2? kinase HRI is a novel therapeutic target in MM that can augment current treatment strategies.
CAS:
– [1257423-87-2]
Formular:
– C13H8Cl2N4OS
SMILES:
– O=C(NC1=CC=C(Cl)C(Cl)=C1)NC2=CC=C3N=NSC3=C2
