Product Details
Product Name:
– CP-868596 (Crenolanib)
Catalog Number:
– D5159
Field of Application:
– Crenolanib (CP-868596) is a potent and selective inhibitor of PDGFR?/? with Kd of 2.1 nM/3.2 nM, also potently inhibits FLT3, sensitive to D842V mutation not V561D mutation, >100-fold more selective for PDGFR than c-Kit, VEGFR-2, TIE-2, FGFR-2, EGFR, erbB
CAS:
– [670220-88-9]
Formular:
– C26H29N5O2
SMILES:
– NC1CCN(C2=CC=CC3=C2N=C(N4C5=CC=C(C=C5N=C4)OCC6(COC6)C)C=C3)CC1
