Product Details
Product Name:
– CU-115
Catalog Number:
– D42507
Field of Application:
– CU115 is a potent TLR8 antagonist (IC50=1.04 ?M), and shows selective for TLR8 over TLR7 (IC50=>50 ?M). CU 115 decreases TNF-? and IL-1? production activated by R-848 in THP-1 cells.
CAS:
– [2471982-20-2]
Formular:
– C21H11F7INO2
SMILES:
– O=C(NC1=CC=C(OC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C=C1)C3=C(I)C=CC=C3F
