– DBCO-PEG4-Ahx-DM1 is a drug-linker conjugate composed of a potent microtubulin?inhibitor?DM1 and a linker DBCO-PEG4-Ahx to make antibody drug conjugate (ADC). Mertansine (DM1) is a?microtubulin?inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery.