Product Details
Product Name:
– DBPR112
Catalog Number:
– D26184
Field of Application:
– DBPR112 is a potent EGFR mutation inhibitor against EGFRL858R/T790M double mutations with IC50 of 48 nM and also exhibits 10-fold potency better than Osimertinib, against EGFR and HER2 exon 20 insertion mutations.
CAS:
– [1226549-49-0]
Formular:
– C32H31N5O3
SMILES:
– O1C2C(=C(N=C([H])N=2)N([H])[C@]([H])(C([H])([H])O[H])C2C([H])=C([H])C([H])=C([H])C=2[H])C(C2C([H])=C([H])C([H])=C(C=2[H])N([H])C(/C(/[H])=C([H])/C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=O)=C1C1C([H])=C([H])C([H])=C([H])C=1[H]
