Product Details
Product Name:
– Divarasib
Catalog Number:
– D58312
Field of Application:
– Divarasib (GDC-6036) is an orally bioavailable, highly potent, and selective KRAS G12C inhibitor with an IC50 of <0.01 ?M. Divarasib covalently binds to the switch II (SW-II) pocket of KRAS G12C and irreversibly locks it in the inactive GDP-bound state.
CAS:
– [2417987-45-0]
Formular:
– C29H32CLF4N7O2
SMILES:
– C(=C)C(N1CC(C)N(C2=NC(OCC3N(C)CCC3)=NC3C2=CC(=C(C2N=C(N)C=C(C)C=2C(F)(F)F)C=3F)Cl)CC1)=O
