Product Details
Product Name:
– Doramapimod (BIRB-796)
Catalog Number:
– D7836
Field of Application:
– BIRB 796 (Doramapimod) is a highly selective p38? MAPK inhibitor with Kd of 0.1 nM, 330-fold greater selectivity versus JNK2, weak inhibition for c-RAF, Fyn and Lck, insignificant inhibition of ERK-1, SYK, IKK2, ZAP-70, EGFR, HER2, PKA, PKC, PKC?/?/?.
CAS:
– [285983-48-4]
Formular:
– C31H37N5O3
SMILES:
– O=C(NC1=CC(C(C)(C)C)=NN1C2=CC=C(C)C=C2)NC3=C4C=CC=CC4=C(OCCN5CCOCC5)C=C3
