Product Details
Product Name:
– DU011
Catalog Number:
– D70368
Field of Application:
– DU011 is a noncanonical anti-infective agent and small-molecule inhibitor of capsule biogenesis, targets MprA (Kd=30 nM), a MarR family transcriptional repressor of multidrug efflux pumps, inhibits capsule expression in E. coli.
DU011 does not alter Escherichia coli antibiotic resistance and has significantly enhanced inhibition of capsule expression, compared with other proposed MprA ligands, such as salicylate and 2,4-dinitrophenol (DNP).
CAS:
– [890818-51-6]
Formular:
– C20H15F2NO4S
SMILES:
– O=C(C1=C(NC(C2=C(F)C=CC=C2F)=O)C=C(C3=CC=C(OCC)C=C3)S1)O
