Product Details
Product Name:
– eFT508(Tomivosertib)
Catalog Number:
– D9755
Field of Application:
– Tomivosertib (eFT-508) is a potent and selective MNK1/2 inhibitor with IC50s of 2.4 nM and 1 nM, respectively. It potentially results in decreased tumor cell proliferation and tumor growth. Tomivosertib (eFT-508) inhibits eIF4E phosphorylation and dramatically downregulates PD-L1 protein abundance.
CAS:
– [1849590-01-7]
Formular:
– C17H20N6O2
SMILES:
– C1=NC(N)=CC(NC2C(=O)N3C4(CCCCC4)NC(=O)C3=C(C)C=2)=N1
