Evofosfamide(TH-302)

SKU D7689-100 mg Category

Product Details

Product Name:

– Evofosfamide(TH-302)

Catalog Number:

– D7689

Field of Application:

– TH-302 is selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM, demonstrates 270-fold enhanced cytotoxicity under hypoxia versus their potency under aerobic conditions, stable to cytochrome P450 metabolism.

CAS:

– [918633-87-1]

Formular:

– C9H16Br2N5O4P

SMILES:

– CN1C(=CN=C1[N+](=O)[O-])COP(=O)(NCCBr)NCCBr

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