Product Details
Product Name:
– GAT1508
Catalog Number:
– D70426
Field of Application:
– GAT1508 (GAT-1508) is a potent, specific activator for brain-expressed GIRK1/2 channels (EC50=75 nM), specifically activates the brain GIRK1/2 over the cardiac GIRK1/4;
GAT1508 is an allosteric modulator of channelphosphatidylinositol 4,5-bisphosphate interactions.
GAT1508 effectively extinguished conditioned fear in rodents and lacked cardiac and behavioral side effects, suggesting its potential for use in pharmacotherapy for post-traumatic stress disorder.
CAS:
– [2397594-21-5]
Formular:
– C15H13BRN4OS
SMILES:
– C1=CC=CC(N2N=C(C=C2NC(=O)NC2SC(Br)=CC=2)C)=C1
