GDC-0214(GDC0214)

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SKU D12547-100 mg Category

Product Details

Product Name:

– GDC-0214(GDC0214)

Catalog Number:

– D12547

Field of Application:

– GDC0214 is a potent, selective inhalable and lung-restricted inhibitor of JAK1 with IC50 of 8.52 nM, displays 6.3/704/28 fold selectivity over JAK2/JAK3/TYK2.

CAS:

– [1831144-46-7]

Formular:

– C28H28ClF2N9O3

SMILES:

– C12=C(C(NC3=CN(CC(N4CCC(N(CCC#N)C)CC4)=O)N=C3C3=CC(Cl)=CC=C3OC(F)F)=O)C=NN1C=CC=N2

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