Product Details
Product Name:
– GDC-2394
Catalog Number:
– D72265
Field of Application:
– GDC-2394 is an orally active and selective NLRP3 inhibitor, and also inhibits IL-1? with IC50s of 0.4 ?M (human IL-1?) and 0.1 ?M (mouse IL-1?). GDC-2394 inhibits NLRP3-induced caspase-1 activity without inhibiting NLRC4-dependent inflammasome activation.
CAS:
– [2238822-07-4]
Formular:
– C20H25N5O4S
SMILES:
– O=S(C1=C2OC[C@@H](NC)CN2N=C1)(NC(NC3=C4CCCC4=CC5=C3CCC5)=O)=O
