Product Details
Product Name:
– GR-127935
Catalog Number:
– D70441
Field of Application:
– GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist with pKi of 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptor; displays >100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types; blocks porcine carotid vascular response to sumatriptan in vivo; orally bioavailable and centrally active.
CAS:
– [148672-13-3]
Formular:
– C29H31N5O3
SMILES:
– CC1=CC(=CC=C1C2=CC=C(C=C2)C(=O)NC3=CC(=C(C=C3)OC)N4CCN(C)CC4)C5=NOC(=N5)C
