Product Details
Product Name:
– HaloPROTAC-E
Catalog Number:
– D65880
Field of Application:
– HaloPROTAC-E is a novel HaloPROTAC potent degrader, inducing reversible degradation of two endosomally localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM, remarkably selective inducing only degradation of the Halo tagged endogenous VPS34 complex (VPS34, VPS15, Beclin1, and ATG14) and no other proteins were significantly degraded.
CAS:
– [2365478-58-4]
Formular:
– C39H56CLN5O8S
SMILES:
– C(C1(CC1)C#N)(=O)N[C@@H](C(C)(C)C)C(N1C[C@H](O)C[C@H]1C(=O)NCC1C=CC(C2SC=NC=2C)=CC=1OCCOCCOCCOCCCCCCCl)=O
