HC-067047

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SKU D11416-100 mg Category Small Compound

Size

10 mM * 1 mL in DMSO
100 mg
250 mg
1 g

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Product Details

Product Name:

– HC-067047

Catalog Number:

– D11416

Field of Application:

– HC-067047 is a potent and selective TRPV4 antagonist with IC50 values of 48 ± 6 nM, 133 ± 25 nM, and 17 ± 3 nM, respectively in human, rat, and mouse. Also inhibits the endogenous TRPV4-mediated response to 4?-PDH (IC50 = 22 nM).

CAS:

– [883031-03-6]

Formular:

– C26H28F3N3O2

SMILES:

– FC(C1C([H])=C([H])C([H])=C(C=1[H])N([H])C(C1C([H])=C(C2C([H])=C([H])C([H])=C([H])C=2[H])N(C=1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=O)(F)F