Product Details
Product Name:
– HS014
Catalog Number:
– D41671
Field of Application:
– HS014 is a potent and selective melanocortin-4 (MC4) receptor antagonist, with Kis of 3.16, 108, 54.4 and 694 nM for human MC4, MC1, MC3 and MC5 receptors, respectively. HS014 modulates the behavioral effects of morphine in mice. HS014 increases food intake in free-feeding rats.
CAS:
– [207678-81-7]
Formular:
– C71H94N20O17S2
SMILES:
– CC(N[C@H]1CSSC[C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](NC([C@@H](NC([C@@H](NC1=O)CCC(O)=O)=O)CC2=CN=CN2)=O)CC3=CC4=CC=CC=C4C=C3)=O)CCCNC(N)=N)=O)CC5=CNC6=CC=CC=C56)=O)=O)C(N7CCC[C@H]7C(N8CCC[C@H]8C(N[C@H](C(N[C@@H](C(N)=O)CC(O)=O)=O)CCCCN)=O)=O)=O)=O
