Product Details
Product Name:
– INDY
Catalog Number:
– D28231
Field of Application:
– INDY is a potent and ATP-competitive Dyrk1A and Dyrk1B inhibitor with IC50s of 0.24 ?M and 0.23 ?M, respectively. INDY binds in the ATP pocket of the enzyme and has a Ki value of 0.18 ?M for Dyrk1A. INDY sharply reduces the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma (GBM) cell lines and neural progenitor cells.
CAS:
– [1169755-45-6]
Formular:
– C12H13NO2S
SMILES:
– CC(/C=C1SC2=CC=C(O)C=C2N1CC)=O
