Product Details
Product Name:
– IRES-J007
Catalog Number:
– D22995
Field of Application:
– IRES-J007 ia an improved IRES inhibitor that blocks IRES-hnRNP A1 binding; binds to a small pocket structure within the RRM-containing fragment of hnRNP A1 (UP1 fragment), inhibits cyclin D1 and c-MYC IRES activity to a greater extent compared with C11 (IRES-C11); significantly reduces tumor growth of GBM xenografts in mice, and markedly reduces the mRNA translational state of cyclin D1 and c-MYC transcripts combined with PP242.
CAS:
– [155514-72-0]
Formular:
– C17H15NO4
SMILES:
– O(C([H])([H])[H])C1C([H])=C(C([H])=C([H])C=1C([H])([H])N1C(C2=C([H])C([H])=C([H])C([H])=C2C1=O)=O)OC([H])([H])[H]
