Product Details
Product Name:
– KS176
Catalog Number:
– D9256
Field of Application:
– KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 ?M in Pheo A and Hoechst 33342 assays respectively). Displays no inhibitory activity against P-gp or MRP1.
CAS:
– [1253452-78-6]
Formular:
– C22H19N3O5
SMILES:
– O=C(C1=C(NC(C2=CC=C([N+]([O-])=O)C=C2)=O)C=CC=C1)NC3=CC=C(CCO)C=C3
