Product Details
Product Name:
– LDE225 Diphosphate
Catalog Number:
– D7185
Field of Application:
– LDE225 (NVP-LDE225) is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively. Phase 3.
CAS:
– [1218778-77-8]
Formular:
– C26H32F3N3O11P2
SMILES:
– N1(C[C@H](C)O[C@H](C)C1)C1=CC=C(C=N1)NC(=O)C1C=CC=C(C2C=CC(=CC=2)OC(F)(F)F)C=1C.P(O)(O)(O)=O.P(O)(O)(O)=O
