Product Details
Product Name:
– LMTK3 inibitor C28
Catalog Number:
– D65898
Field of Application:
– LMTK3-IN-1 (compound C28) is an ATP-competitive inhibitor of lemur tyrosine kinase 3 (LMTK3) (Kd=2.5 ?M)?that acts by degrading LMTK3 via the ubiquitin-proteasome pathway. LMTK3-IN-1 shows anticancer activity in a variety of cancer cell lines and in vivo BC mouse models. LMTK3-IN-1 induces apoptosis in BC cell lines at 10-20 ?M.
CAS:
– [2764850-23-7]
Formular:
– C18H11F3N4O
SMILES:
– O(C1=CC=CC(C2=CN=C3C=CC(C4=CC=NC=C4)=NN23)=C1)C(F)(F)F
