Product Details
Product Name:
– MCI-INI-3
Catalog Number:
– D70590
Field of Application:
– MCI-INI-3 is a potent, selective, competitive inhibitor of ALDH1A3 (Ki=0.55 uM), shows poor inhibitory effect on the structurally related isoform ALDH1A1 (>140-fold selectivity).MCI-INI-3 also displays on inhibition against six isoforms of ALDH (ALDH16A1, ALDH7A1, ALDH9A1, ALDH2, ALDH1B1, ALDH18A1).MCI-INI-3 demonstrates selective binding to ALDH1A3 in glioma stem cell lysates, inhibits ALDH activity and affects RA synthesis in cells.
CAS:
– [1011366-31-6]
Formular:
– C21H15N3O4
SMILES:
– C12=CC(C3=CC=CC=C3)=NN1C(C(OC)=O)=CC(C1=CC=C3OCOC3=C1)=N2
