Product Details
Product Name:
– Micafungin
Catalog Number:
– D60080
Field of Application:
– Micafungin, also known as FK463, is a polyene antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis. It inhibits the production of beta-1,3-glucan, an essential component of fungal cell walls. It received final approval from the U.S. Food and Drug Administration (FDA) on March 16, 2005. Micafungin works by way of concentration-dependent inhibition of 1,3-beta-D-glucan synthase resulting in reduced formation of 1,3-beta-D-glucan, which is an essential polysaccharide comprising one-third of the majority of Candida spp. cell walls. This decreased glucan production leads to osmotic instability and thus cellular lysis.
CAS:
– [235114-32-6]
Formular:
– C56H71N9O23S
SMILES:
– CCCCCOC1=CC=C(C2=CC(C3=CC=C(C(N[C@H]4C[C@H]([C@H](NC([C@@H]5[C@H]([C@H](CN5C([C@H]([C@@H](CC(N)=O)O)NC([C@H]([C@@H]([C@H](C6=CC(OS(=O)(O)=O)=C(O)C=C6)O)O)NC([C@@H]7C[C@H](CN7C([C@H]([C@H](O)C)NC4=O)=O)O)=O)=O)=O)C)O)=O)O)O)=O)C=C3)=NO2)C=C1
