– MRT-10 is a seven-transmembrane receptor smoothened (Smo) antagonist with an IC50 of 0.65 ?M in the micromolar range in various Hedgehog (Hh) assays. MRT-10 binds to the Smo receptor at the level of the Bodipycyclopamine binding site. MRT-10 can be used for the research of cancer[1][2].