Product Details
Product Name:
– Niraparib tosylate
Catalog Number:
– D9576
Field of Application:
– MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.
CAS:
– [1038915-73-9]
Formular:
– C26H28N4O4S
SMILES:
– O=C(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C12)N.O=S(C5=CC=C(C)C=C5)(O)=O
