Product Details
Product Name:
– NMDAR/TRPM4-IN-2
Catalog Number:
– D66079
Field of Application:
– NMDAR/TRPM4-IN-2 (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. NMDAR/TRPM4-IN-2 shows neuroprotective activity. NMDAR/TRPM4-IN-2 prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 ?M. NMDAR/TRPM4-IN-2 protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss.
CAS:
– [2243506-33-2]
Formular:
– C11H18BRCLN2
SMILES:
– C(C1C=CC=C(Br)C=1)N(CC)CCN.Cl
