Product Details
Product Name:
– NNC 55-0396 2HCl
Catalog Number:
– D22380
Field of Application:
– NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and > 100 ?M for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells. IC50 value: 6.8 nMTarget: Cav3.1 T-type channelNNC 55-0396 can be an essential tool in preventing human ovarian cancer cell proliferation as a result of its ability to inhibit the function of T-type Ca2+ channels. It is believed that NNC 55-0396 may functions by dissolving in or passing through the plasma membrane of cells.
CAS:
– [357400-13-6]
Formular:
– C30H40Cl2FN3O2
SMILES:
– C=NN
