NVS-STG2

SKU D60500-5mg Category
In Stock

Product Details

Product Name:

– NVS-STG2

Catalog Number:

– D60500

Field of Application:

– NVS-STG2 is a small molecule STING agonist with AC50 of 5.2 ?M. NVS-STG2 induces the high-order oligomerization of human STING by binding to a pocket between the transmembrane domains of the neighboring STING dimers and elicit potent STING-mediated immune responses in cells and antitumor activities in animal models.

Formular:

– C25H33NO5

SMILES:

– COC1=C(C=CC(C(O)=O)=C1)NCC2=CC=C(C=C2)C3(OCC(C)(CO3)C)C(C)(C)C

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