Product Details
Product Name:
– Orvepitant maleate
Catalog Number:
– D28435
Field of Application:
– Orvepitant maleate (GW823296 maleate) is potent, selective, orally active and well-tolerated neurokinin-1 receptor (NK-1) antagonist with a pKi of 10.2 for human neurokinin-1 receptor. Orvepitant maleate can across the blood-brain barrier. Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment.
CAS:
– [579475-24-4]
Formular:
– C35H39F7N4O6
SMILES:
– FC1C([H])=C([H])C(=C(C([H])([H])[H])C=1[H])[C@@]1([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N1C(N(C([H])([H])[H])[C@]([H])(C([H])([H])[H])C1C([H])=C(C(F)(F)F)C([H])=C(C(F)(F)F)C=1[H])=O)N1C([H])([H])C([H])([H])N2C(C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])=O.O([H])C(/C(/[H])=C(/[H])C(=O)O[H])=O
