Product Details
Product Name:
– PARP-1-IN-2
Catalog Number:
– D66008
Field of Application:
– PARP-1-IN-2 (compound 11g) is a potent and BBB-penetrated PARP1 inhibitor, with an IC50 of 149 nM. PARP1-IN-2 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549. PARP1-IN-2 can induce A549 cells apoptosis.
CAS:
– [684234-55-7]
Formular:
– C22H15CL2N3O2
SMILES:
– ClC1C([H])=C([H])C(=C([H])C=1[H])C1C2=C([H])C([H])=C([H])C([H])=C2C(N(C([H])([H])C(N([H])C2C([H])=C([H])C([H])=C(C=2[H])Cl)=O)N=1)=O
