Product Details
Product Name:
– Pexmetinib(ARRY-614)
Catalog Number:
– D8174
Field of Application:
– Pexmetinib is a potent Tie-2 and p38 MAPK dual inhibitor, with IC50s of 1 nM, 35 nM and 26 nM for Tie-2, p38? and p38?, respectively, and can be used in the research of acute myeloid leukemia.
CAS:
– [945614-12-0]
Formular:
– C31H33FN6O3
SMILES:
– O=C(NCC1=CC(F)=CC=C1OC2=CC3=C(N(CCO)N=C3)C=C2)NC4=CC(C(C)(C)C)=NN4C5=CC=C(C)C=C5
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