Product Details
Product Name:
– PF-05221304(Clesacostat)
Catalog Number:
– D44535
Field of Application:
– PF-05221304 is an orally bioavailable, liver-directed and dual ACC1 (and ACC2) inhibitor with IC50s of 7.5 nM for rat ACC1, 8.2 nM for rat ACC2, 12.4 nM for human ACC1 and 8.7 nM for human ACC2. PF-05221304 is a substrate for organic anion transport polyp
CAS:
– [1370448-25-1]
Formular:
– C28H30N4O5
SMILES:
– O=C(O)C1=CC=C(C2=NC(OC)=CC(C(N3CCC(C4)(CC3)CC5=C(N(C(C)C)N=C5)C4=O)=O)=C2)C=C1
