Product Details
Product Name:
– PF-06843195
Catalog Number:
– D44213
Field of Application:
– PF-06843195 is a highly selective PI3K? inhibitor with an IC50 of 18 nM in Rat1 fibroblasts. The Kis of PF-06843195 for PI3K? and PI3K? in biochemical kinase assay are less than 0.018 nM and 0.28 nM, respectively. PF-06843195 has great suppression of the PI3K/mTOR signaling pathway and durable antitumor efficacy.
CAS:
– [2067281-51-8]
Formular:
– C20H25F3N8O4
SMILES:
– FC1=C(C2=C([H])N=C(N([H])[H])N=C2[H])N=C(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N=C1N([H])[C@]1(C([H])([H])O[H])C([H])([H])N(C(=O)OC([H])([H])C([H])(F)F)C([H])([H])C1([H])[H]
