Product Details
Product Name:
– PF-5274857
Catalog Number:
– D12373
Field of Application:
– PF-5274857 is a potent and selective Smoothened (Smo) antagonist, inhibits Hedgehog (Hh) signaling with IC50 and Ki of 5.8 nM and 4.6 nM, respectively, and can penetrate the bloodbrain barrier.
CAS:
– [1373615-35-0]
Formular:
– C20H25ClN4O3S
SMILES:
– O=C(N1CCN(C2=NC=C(Cl)C(C3=NC=C(C)C=C3C)=C2)CC1)CCS(=O)(C)=O
